Clinical and hematological profile in a newborn cohort with hemoglobin SC
نویسندگان
چکیده
منابع مشابه
Clinical and hematological profile in a newborn cohort with hemoglobin SC.
OBJECTIVES Hemoglobin SC is the second most common variant of sickle-cell disease worldwide, after hemoglobin SS. The objectives of the study were to describe the clinical and laboratory characteristics of hemoglobin SC disease in children from a newborn screening program and treated at a blood center. METHODOLOGY This study assessed a cohort of 461 infants born between 01/01/1999 and 12/31/2...
متن کاملClinical, hematological and genetic data of a cohort of children with hemoglobin SD
INTRODUCTION The hemoglobin FSD is very uncommon in newborn screening programs for sickle cell disease. In the program of Minas Gerais, Brazil, the clinical course of children with hemoglobin SD was observed to be heterogeneous. The objective of this study was to estimate the incidence (1999-2012) and to describe the natural history of a cohort of newborns with hemoglobin SD. METHODS Isoelect...
متن کاملComments on: “Clinical, hematological and genetic data of a cohort of children with hemoglobin SD”☆
Sickle cell disease (SCD) is a group of genetic conditions related to the presence of a sickle hemoglobin (Hb S) mutation (HBB:c.20A>T). People with SCD can be homozygous for Hb S or can have compound heterozygosity for Hb S with other gene mutations.1,2 Some hematologic features of SCD are listed in Table 1, but rare genotypes can also be found. Since the concentration of Hb S is a pathophysio...
متن کاملDyspnea with hemoglobin SC disease.
BUMC PROCEEDINGS 2002;15:86–90 CASE PRESENTATION LINDA S. BANG, MD: A 41-year-old African American woman with sickle cell disease presented to the Baylor University Medical Center emergency department with dyspnea and dry cough for 3 weeks and back, leg, and chest pain for 2 to 3 days. The hemoglobin SC disease had been first diagnosed during pregnancy. Pleural tuberculosis with a left-sided ef...
متن کاملHemoglobin SC smear recorded with a smartphone
Taking photographs of microscope slides generally requires expensive equipment and a lot of effort. We demonstrate a technique to take clear, focused pictures of microscope slides with a smartphone. This could facilitate exchange of information between providers, allow for quick second opinions, and improve patient care.
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ژورنال
عنوان ژورنال: Jornal de Pediatria
سال: 2018
ISSN: 0021-7557
DOI: 10.1016/j.jped.2017.09.010